{"id":344,"date":"2024-05-08T16:31:28","date_gmt":"2024-05-08T08:31:28","guid":{"rendered":"https:\/\/we-cip.com\/?post_type=members&#038;p=344"},"modified":"2024-07-31T11:19:42","modified_gmt":"2024-07-31T03:19:42","slug":"jun-a","status":"publish","type":"members","link":"http:\/\/we-cip.com\/zh\/members\/jun-a\/","title":{"rendered":"\u963f\u4fca"},"content":{"rendered":"<p>Jun obtained his PhD degree from Nankai University, School of Life Sciences, and majored in Genetics (2017-2021). During his doctoral study, he mainly focused on the molecular signatures predictive of recurrence-free survival (RFS) and castration resistance in prostate cancer (PCa), he applied a machine learning algorithm to develop a predictive diagnostic and a prognostic model using castration-resistant PCa (CRPC)-associated genes. In addition, he investigated the role of MCM4, a minichromosome maintenance protein, in the development of CRPC. In September 2021, Jun joined the Guomics team as a postdoctoral researcher for proteomic big data research.<\/p>\n<p>Representative Publications<\/p>\n<p>1. A, J., Zhang, B., Zhang, Z., Hu, H., &amp; Dong, J. T. (2021). Novel Gene Signatures Predictive of Patient Recurrence-Free Survival and Castration Resistance in Prostate Cancer. Cancers.<\/p>\n<p>2.Fu, C., An, N., Liu, J., A, J., Zhang, B., Liu, M., Zhang, Z., Fu, L., Tian, X., Wang, D., &amp; Dong, J. T. (2020). The transcription factor ZFHX3 is crucial for the angiogenic function of hypoxia-inducible factor 1\u03b1 in liver cancer cells. The Journal of biological chemistry<\/p>\n<p>3.Wu, R., Fang, J., Liu, M., A, J., Liu, J., Chen, W., Li, J., Ma, G., Zhang, Z., Zhang, B., Fu, L., &amp; Dong, J. T. (2020). SUMOylation of the transcription factor ZFHX3 at Lys-2806 requires SAE1, UBC9, and PIAS2 and enhances its stability and function in cell proliferation. The Journal of biological chemistry.<\/p>\n","protected":false},"featured_media":467,"template":"","members_category":[13],"class_list":["post-344","members","type-members","status-publish","has-post-thumbnail","hentry","members_category-research-scientist"],"acf":[],"_links":{"self":[{"href":"http:\/\/we-cip.com\/zh\/wp-json\/wp\/v2\/members\/344","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/we-cip.com\/zh\/wp-json\/wp\/v2\/members"}],"about":[{"href":"http:\/\/we-cip.com\/zh\/wp-json\/wp\/v2\/types\/members"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/we-cip.com\/zh\/wp-json\/wp\/v2\/media\/467"}],"wp:attachment":[{"href":"http:\/\/we-cip.com\/zh\/wp-json\/wp\/v2\/media?parent=344"}],"wp:term":[{"taxonomy":"members_category","embeddable":true,"href":"http:\/\/we-cip.com\/zh\/wp-json\/wp\/v2\/members_category?post=344"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}