Jun A


Jun obtained his PhD degree from Nankai University, School of Life Sciences, and majored in Genetics (2017-2021). During his doctoral study, he mainly focused on the molecular signatures predictive of recurrence-free survival (RFS) and castration resistance in prostate cancer (PCa), he applied a machine learning algorithm to develop a predictive diagnostic and a prognostic model using castration-resistant PCa (CRPC)-associated genes. In addition, he investigated the role of MCM4, a minichromosome maintenance protein, in the development of CRPC. In September 2021, Jun joined the Guomics team as a postdoctoral researcher for proteomic big data research.

Representative Publications

1. A, J., Zhang, B., Zhang, Z., Hu, H., & Dong, J. T. (2021). Novel Gene Signatures Predictive of Patient Recurrence-Free Survival and Castration Resistance in Prostate Cancer. Cancers.

2.Fu, C., An, N., Liu, J., A, J., Zhang, B., Liu, M., Zhang, Z., Fu, L., Tian, X., Wang, D., & Dong, J. T. (2020). The transcription factor ZFHX3 is crucial for the angiogenic function of hypoxia-inducible factor 1α in liver cancer cells. The Journal of biological chemistry

3.Wu, R., Fang, J., Liu, M., A, J., Liu, J., Chen, W., Li, J., Ma, G., Zhang, Z., Zhang, B., Fu, L., & Dong, J. T. (2020). SUMOylation of the transcription factor ZFHX3 at Lys-2806 requires SAE1, UBC9, and PIAS2 and enhances its stability and function in cell proliferation. The Journal of biological chemistry.